04.10.2023 13:17:44

Freeline Reports Positive Data From First Cohort Of Phase 1/2 GALILEO-1 Trial Of FLT201

(RTTNews) - Freeline Therapeutics Holdings plc (FRLN) reported positive initial safety, tolerability and enzyme activity data from the ongoing Phase 1/2 GALILEO-1 trial evaluating FLT201, its gene therapy candidate, in Gaucher disease. The company said, in addition to demonstrating a favorable safety and tolerability profile, data from the first two patients in GALILEO-1 showed that a single infusion of FLT201 led to several hundred-fold increases in GCase activity in plasma and normalization of GCase activity in leukocytes.

Michael Parini, CEO, said: "These clinical data show the preclinical data are starting to translate, and we are committed to expeditiously advancing FLT201."

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