Recent Developments in the Pharmaceutical Industry

NEW YORK, September 5, 2017 /PRNewswire/ --

According to a report by the Pharmaceutical Commerce (Market research firm Evaluate Pharma) in its annual World Preview report, projects a global growth rate for the pharma industry of 6.3% CAGR through 2022. By 2020, the pharma industry is estimated to be valued at about $1.12 trillion. The report indicates that according to Evaluate, the industry will rise at a faster rate during 2016-2020 period, then slow down because major patent expirations will come into effect. According to Evaluate, the prescription sales will reach $1.006 trillion in 2022, generics sales will increase from $73 billion in 2015 to $115 billion in 2022. There are some concerns regarding the growth potential of the industry, which is the result of political uncertainties in the developed world, including Brexit and rising skepticism in the U.S. over the worth of pharmaceuticals due to consistently increasing prices. Cosmos Holdings Inc. (OTC: COSM), CytRx Corporation (NASDAQ: CYTR), Palatin Technologies, Inc. (NYSE: PTN), Aralez Pharmaceuticals Inc. (NASDAQ: ARLZ), Immune Pharmaceuticals Inc. (NASDAQ: IMNP)

In the meantime, a report by Mordor Intelligence estimates that the global pharmaceutical contract manufacturing market will reach USD 94.38 billion by 2022, at a CAGR of 6.36% during the forecast period, from 2017 to 2022. Contract manufacturing refers to the outsourcing of certain production activities to third-party vendors. Pharmaceutical companies give the chemical formula of a drug to be manufactured to pharmaceutical contract manufacturers (CMO). "Major factors driving the growth of CMOs in the pharmaceutical industry are the growing need for state-of-the-art processes and production technologies, which have proven highly effective in meeting regulatory requirements," according to Mordor Intelligence.

Cosmos Holdings Inc. (OTCQB: COSM) is a fully reporting Pharmaceutical Holding Company that specializes, through its subsidiaries, in the wholesale of pharmaceutical products throughout Europe. Earlier today the company announced, "that it has engaged ROTH Capital Partners, LLC ("ROTH"), a leading investment banking and securities firm, to provide financial advisory services, in particular related to evaluating multiple financing options. ROTH will also focus on assisting the Company in creating and executing new strategies for maximizing shareholder value through its full scope of investment banking services. The Company does not have a defined timeline for a financing and cannot provide any assurance whether or when a financing will be announced or consummated."

About Cosmos Holdings Inc. - Cosmos Holdings Inc. is a pharmaceutical company focused on identifying, acquiring, developing, and commercializing medicines to improve patients' lives and outcomes. The Company has a trans-European network of more than 60 clients and vendors in Germany, the United Kingdom, Italy, France, Sweden, Ireland, Denmark, Poland, Netherlands, and Greece. Cosmos Holdings has offices and distribution centers in Thessaloniki, Greece and In Harlow, UK. More information is available at http://www.cosmosholdingsinc.com.

Palatin Technologies, Inc. (NYSE: PTN) is a biopharmaceutical company developing targeted, receptor-specific peptide therapeutics for the treatment of diseases with significant unmet medical need and commercial potential. On May 16, 2017, the company announced results for its third quarter ended March 31, 2017. Palatin reported a net loss of $(3.6) million, or $(0.02) per basic and diluted share, for the quarter ended March 31, 2017, compared to a net loss of $(12.7) million, or $(0.08) per basic and diluted share, for the same period in 2016. Total operating expenses for the quarter ended March 31, 2017 were $13.8 million compared to $12.1 million for the comparable quarter of 2016. The increase in operating expenses was predominately attributable to professional services incurred related to closing our license agreement with AMAG.    

CytRx Corporation (NASDAQ: CYTR) is a biopharmaceutical company specializing in research and clinical development of novel anti-cancer drug candidates that employ linker technologies to enhance the accumulation and release of drug at the tumor. On July 28, 2017, the company announced that it has entered into a global strategic license with NantCell, Inc., for the exclusive rights to develop and commercialize aldoxorubicin for all indications. NantCell, a private subsidiary of NantWorks, LLC, is a clinical stage immuno-oncology company focused on developing novel molecularly targeted therapeutics including antibody, T-cell and NK cell based treatments for patients with cancer. 

Aralez Pharmaceuticals Inc. (NASDAQ: ARLZ) is a global specialty pharmaceutical company focused on delivering meaningful products to improve patients' lives while creating shareholder value by acquiring, developing and commercializing products primarily in cardiovascular, pain and other specialty areas. Recently, the company announced financial results for the second quarter and first half of 2017. The Company also highlighted certain corporate and commercial updates. On June 27, 2017, the Company announced that the United States District Court for the District of New Jersey upheld the validity of two patents covering Vimovo® owned by a subsidiary of Aralez and licensed to Horizon Pharma, and further held that each defendant would infringe at least one of the two Aralez subsidiary's patents with their proposed generic naproxen/esomeprazole magnesium products. 

Immune Pharmaceuticals Inc. (NASDAQ: IMNP) is dedicated to alleviating the burden of patients suffering from autoimmune diseases by developing novel immunotherapeutic agents. Immune's lead product candidate, bertilimumab, is in Phase 2 clinical development for bullous pemphigoid, an orphan autoimmune dermatological condition, and for ulcerative colitis. The company recently announced the publication of clinical trial results on the use of Ceplene for relapse prevention in patients with acute myeloid leukemia. The results were published in the leading hematology journal, Leukemia, published by Springer Nature. Investigators from the Universities of Gothenburg, Sweden and Rome, Italy reported that functional NK cells are clinically relevant anti-leukemic effector cells in AML patients who received treatment with Ceplene/IL-2.

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