03.03.2025 16:20:21

Molecular Hiving™ for Sustainable Peptide Synthesis

As the demand for peptide-based therapeutics continues to grow, the need for innovative, cost-efficient, and environmentally friendly manufacturing technologies becomes increasingly critical. Traditional solid-phase peptide synthesis (SPPS) methods, while effective, pose significant environmental and scalability challenges. Our white paper explores Molecular Hiving (MH), a groundbreaking technology that combines the benefits of liquid-phase peptide synthesis (LPPS) with efficient, aqueous-based purification. Developed by Professor Kazuhiro Chiba and exclusively implemented at scale by Bachem, MH offers a sustainable, streamlined alternative to SPPS, aligning with our commitment to green chemistry and sustainable manufacturing practices. Innovative Manufacturing Techniques: Discover how MH offers a sustainable and scalable alternative to SPPS, enabling efficient peptide production.Enhanced Process Efficiency: Understand the improvements in process mass intensity (PMI), solvent consumption, and productivity achieved through MH.Sustainable Solutions: Explore how MH reduces the environmental footprint by minimizing hazardous reagents and solvents.High Purity and Yield: Read about the optimized MH process that ensures high purity and yield with minimal downstream purification.The post Molecular Hiving™ for Sustainable Peptide Synthesis appeared first on Bachem.Weiter zum vollständigen Artikel bei Bachem Holding AG

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