Ipsen and Mayoly Spindler enter into cross- promotion agreement for primary care activities in France

Regulatory News:

Ipsen (Paris:IPN)(Euronext: IPN; ADR: IPSEY) and Mayoly Spindler today announced the signing of a cross-promotion agreement for their primary care activities in France. Through the creation of a co-managed commercial platform, the two companies will leverage their complementary competencies and product portfolios.

Mayoly Spindler will benefit from Ipsen’s experience in the promotion of medicines to general practitioners in France, in particular in the fields of gout and gastroenterology. In parallel, Ipsen will benefit from Mayoly Spindler’s experience in pharmacies.

This agreement leverages the complementarity of each company’s product portfolio. In the field of gastroenterology, Meteospasmyl^®, indicated to treat abdominal spasms, is complementary to Ipsen’s product range which includes Smecta^® and Forlax^®. In the field of rheumatology, Colchicine^® will complement Ipsen’s Adenuric^®.

This partnership also reinforces the presence of both companies in pharmacies. Pharmacists will play a key role in the development of safe and responsible self-medication as part of the disease treatment pathway.

Under the terms of the agreement, each company will continue to book the sales of its own products. The partnership will be effective in January 2014.

Marc de Garidel, Chairman and CEO of Ipsen stated: "This agreement demonstrates Ipsen’s ambition to pursue the optimization of its primary care activities, as illustrated by the creation of its global Primary Care Business Unit announced in October. In a challenging French pharmaceutical environment, this partnership sustainably strengthens Ipsen’s presence in primary care in France via portfolio synergies and accelerated access to know-how regarding promotion to pharmacies.”

Jean-Nicolas Vernin, Chairman of Mayoly Spindler added: "We are pleased to build this new partnership with Ipsen: both laboratories own strong primary care products, which are trusted by prescribers. This agreement illustrates the commitment of both companies to develop their primary care activities through an innovative partnership and strong brands, in very complementary indications. ”

About Ipsen

Ipsen is a global specialty-driven pharmaceutical company with total sales exceeding €1.2 billion in 2012. Ipsen’s ambition is to become a leader in specialty healthcare solutions for targeted debilitating diseases. Its development strategy is supported by 3 franchises: neurology, endocrinology and uro-oncology. Moreover, the Group has an active policy of partnerships. Ipsen's R&D is focused on its innovative and differentiated technological platforms, peptides and toxins. In 2012, R&D expenditure totalled close to €250 million, representing more than 20% of Group sales. The Group has close to 4,900 employees worldwide. Ipsen’s shares are traded on segment A of Euronext Paris (stock code: IPN, ISIN code: FR0010259150) and eligible to the "Service de Règlement Différé” ("SRD”). The Group is part of the SBF 120 index. Ipsen has implemented a Sponsored Level I American Depositary Receipt (ADR) program, which trade on the over-the-counter market in the United States under the symbol IPSEY. For more information on Ipsen, visit www.ipsen.com.

About Mayoly Spindler

Mayoly Spindler is an independent French family-run pharmaceutical company which has been able to grow for several decades through effective and recognized pharmaceutical products. Its know-how mainly covers gastroenterology, rheumatology, ENT, and more recently dermocosmetics in order to diversify its activities. Mayoly Spindler has more than 700 employees.

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