25.09.2007 12:45:00
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Plexera Bioscience and MitoSciences Inc. Announce Collaboration on Mitochondrial Array
Plexera Bioscience LLC, a wholly owned subsidiary of Lumera Corporation
(NASDAQ:LMRA), and MitoSciences Inc., developers of antibodies and
assays for understanding mitochondrial function, announced today that
they have entered into an agreement that outlines a commercial path for
an antibody array product which is enabled with Plexera’s
ProteomicProcessor™ and MitoSciences'
proprietary antibodies.
This product development is in conjunction with a separate and
previously announced agreement with the Medical University of South
Carolina in which researchers there are building a protein expression
profiling assay with Mitosciences’ antibodies
and Plexera’s ProteomicProcessor™.
"Changes in mitochondrial proteins are known
to be markers for certain pathologies and many adverse drug effects. We
feel that by combining MitoSciences' well characterized antibodies and
Plexera’s ProteomicProcessor™
we will have an assay that will have significant time and cost
advantages over existing technologies. Perhaps as important will be our
ability to identify and characterize multiple protein markers in one
assay,” said Dr. Craig Beeson, Associate
Professor of Pharmaceutical Sciences at MUSC and the Principle
Investigator on this project.
"We are excited to be working along side of
MitoSciences and believe that combining their content with our detection
platform has very exciting commercial prospects,”
said Dr. Tim Londergan, President and Chief Operating Officer of
Plexera. "This has the potential to become a
mainstream assay in the ADME and toxicology market as pharmaceutical
companies desperately need to find new ways to screen and eliminate
problematic compounds sooner in the process.”
The total U.S. ADME/Tox market was estimated to be $1.1 billion in 2003
and is expected to grow to $2.8 billion by 2009, representing a compound
annual growth rate of 17.2%. Failures of pipeline drugs due to ADME and
toxicology are estimated to be in the 50% to 60% range, making it the
number one reason for preclinical attrition, according to market
research firm Business Insights, Ltd. High-throughout technologies that
quickly and efficiently identify toxic drug compounds promise to
increase the success rate of new pharmaceutical drug development.
"This agreement is the first step in what we
hope to be a long and prosperous commercial relationship with Plexera.
Plexera’s interest in accessing our
proprietary antibody library for use with the ProteomicProcessor™
further validates the market’s demand for
more advanced mitochondrial related assays,”
said John Audette, President of MitoSciences.
About Plexera Bioscience LLC
Plexera Bioscience LLC was established in July of 2007 as wholly owned
subsidiary of Lumera Corporation (NASDAQ:LMRA), and is focused on
providing the life sciences market with tools, content, and methods to
simplify and accelerate proteomic discovery for therapeutic antibodies
as well as predictive biomarkers.
About MitoSciences Inc.
MitoSciences is the leading developer of assays and antibodies for
understanding mitochondrial function, and its products are used
worldwide in life science research, drug development, and diagnostics.
MitoSciences' MitoProfile®
product line includes drug toxicity tests, point-of-care products for
enzymatic testing, and a developing line of multiplexing assays for
mitochondrial diseases and dysfunction.
Certain statements contained in this release are forward-looking
statements that involve a number of risks and uncertainties. Factors
that could cause actual results to differ materially from those
projected in the company's forward-looking statements include the
following: market acceptance of our technologies and products; our
ability to obtain financing; our financial and technical resources
relative to those of our competitors; our ability to keep up with rapid
technological change; government regulation of our technologies; our
ability to enforce our intellectual property rights and protect our
proprietary technologies; the ability to obtain additional contract
awards and to develop partnership opportunities; the timing of
commercial product launches; the ability to achieve key technical
milestones in key products; and other risk factors identified from time
to time in the company's SEC reports, including its Annual Report on
Form 10-K, and its Quarterly Reports on Form 10-Q.
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